Heart Rate Variability Testing (Computerized)
Nerve-Express is a fully automatic, non-invasive computer-based system designed for quantitative assessment of the Autonomic Nervous System (ANS) based on Heart Rate Variability (HRV) analysis.
HRV analysis is based on measuring variability in heart rate; specifically, variability in intervals between R waves – “RR intervals” . These RR intervals are then analyzed by spectral (as in Nerve-Express) or some other form of mathematical analysis (e.g., chaos, wavelet theories). Such mathematical analysis generates multiple parameters; typically 20-30. The problem of SNS-PSNS quantification, which has remained for many years the principal dilemma of HRV analysis, is specifically in reducing all possible variations of these multiple parameters to a quantitative relationship between only two parameters: SNS and PSNS.
Nerve-Express is the first and only system to solve the problem of SNS-PSNS quantification.
This technological breakthrough is achieved by using proprietary algorithms and a new approach based on one of the leading theories of Artificial Intelligence – Marvin Minsky’s Frame Theory.
Nerve-Express objectively and reliably evaluates the state of ANS in “real-time” (up to 24 hours) as well as during Orthostatic test and Valsalva maneuver combined with Deep Breathing. Due to its highly sophisticated HRV analysis,
Nerve-Express is the only system that enables quantification of 74 ANS states with a corresponding qualitative description for each one.
The algorithms used by Nerve-Express have been developed and tested for over twenty years in studies involving more than twenty thousand patients .
Nerve-Express implements a battery of three tests as the most comprehensive and informative combination of tests for ANS purposes:
- Orthostatic test as the initial method for ANS provocation;
- Valsalva maneuver combined with Deep Breathing as the optimal method for revealing the hidden abilities of the Autonomic function and distinguishing between chronic and temporary abnormalities;
- Real-time Nerve-Monitor test as the ultimate method for ANS assessment in long-term therapy, continuous monitoring (especially, under anesthesia/intensive care), research and experimentation.
All three tests may be conducted on a single patient as well as on two patients simultaneously for comparative purposes (with a special cable).